7 MK 677 Side Effects (cancer, gyno, liver, heart, libido)

January 9, 2024 |

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Mk 677 is a growth hormone secretagogue that has been shown to have numerous benefits, such as increased muscle mass and strength, improved bone density, and reduced body fat.

However, like any other substance, Mk 677 has the potential to cause side effects.

In this article, we’ll take a look at some of the most common Mk 677 side effects and how to avoid them.

Why use MK 677?

Many people will have come across a “SARM” called MK 677. This is called Ibutamoren and was developed to increase Growth Hormone production.

Mk 677 Ibutamoren formula

Growth Hormone plays a vital role in adults; unfortunately, some do suffer from low levels.

This can lead to weight gain, muscle loss, and even depression.

While using pure Human Growth Hormone as a replacement is a very effective treatment method, it does have one major drawback. It completely downregulates the endogenous production of Growth Hormone production.

As an improvement on this treatment, scientists figured that instead of simply replacing the Growth Hormone, they could induce more production.

Growth Hormone secretagogues were developed. They will always lead to an increase in Growth Hormone production; the mechanism in which they do this differs from one another.

MK 677, in particular, is known as a ghrelin agonist.

Ghrelin is known as the “hunger” hormone, and more ghrelin would mean more Growth Hormone production.

MK 677 will bind to Ghrelin receptors as an agonist, causing increased Growth Hormone production. If you produce a significant amount of Growth, you can have side effects.

And as we all know, growth hormone is essential for stimulating muscle growth and development.

MK 677 is popular among bodybuilders and athletes because it can help them increase muscle mass and strength while also burning fat. It’s also been shown to improve sleep quality, increase bone density, and boost energy levels.

That said, the chances that these sides will be nearly as severe as pure Growth sides are slim to zero.

7 Dangerous Side effects of MK 677 (Ibutamoren)

Below are MK 677 side effects, explained:

1. Insulin Resistance

The first side effect of MK 677 on our list is insulin resistance.

The mechanism in which Growth Hormone will cause fat loss and muscle gain requires a significant amount of Glucose and Insulin to be dumped into the bloodstream. Glucose can grow muscle tissue and be used for energy in a fat-loss environment.

When this is done too severely or too regularly, it can lead to insulin resistance. This is even more common in diets that are extremely high in carbohydrates.

As anyone with diabetes knows, insulin resistance can be a serious problem. When the body becomes resistant to insulin, it can no longer effectively process sugar, leading to high blood sugar levels. This can lead to a host of health problems, including heart disease, stroke, and kidney damage.

Most people will use something like Metformine (a diabetic drug) to offset this effect.

2. Water Retention

One potential side effect of MK 677 is water retention. This can lead to bloating and weight gain, as well as other uncomfortable symptoms.

Growth Hormones, in general, are known to help you cut fat by a great measure. It also tends to cause a decent amount of water retention. This is likely because Growth Hormone will cause sodium retention in the cells, leading to water retention.

While this side effect is not dangerous, it can be frustrating for those who are trying to lose weight or maintain a healthy lifestyle.

There are a few things that you can do to help reduce water retention if you are taking MK 677.

First, make sure that you are drinking plenty of water. This will help to flush excess water from your system. Second, avoid salty foods, as they can exacerbate water retention.

Finally, try to exercise regularly, as this will help to reduce fluid build-up in the body. If you are concerned about water retention, or if it is interfering with your daily life, talk to your doctor.

They may be able to recommend a different medication or dosage that will reduce this side effect.

3. Carpal Tunnel Syndrome

Carpal Tunnel Syndrome is a medical condition that results from pressure on the median nerve as it passes through the carpal tunnel in the wrist. This pressure can cause numbness, tingling, and pain in the hand and arm.

The symptoms often worsen at night and can interfere with sleep.

While carpal tunnel syndrome is often thought of as a condition that mostly affects office workers who spend hours typing at their computers, it can also be caused by certain medications.  One such medication is MK 677, which is used to treat growth hormone deficiency.

Due to the water retention that happens from sodium retention, you will experience significant swelling around certain areas of the body.

This is particularly true around “smaller” areas such as where joints and wrists are located.

Significant swelling of these areas can lead to the hands and feet developing carpal tunnel syndrome. There is not much you can do about this.

If you are taking MK 677 and experience any hand pain or other symptoms of carpal tunnel syndrome, be sure to consult your doctor.

4. Estrogen and Gyno

For men, one of the most dreaded side effects of taking MK 677 is the development of gyno or man boobs.

This is caused by an increase in estrogen levels, as MK 677 can cause your body to aromatize, or convert, testosterone into estrogen.

If you know anything about hormones, you know that Gyno is developed by an increase in estrogen levels in the male body, usually due to Steroid use (or other drugs). We would not expect Growth Hormone to interact with estrogen or estrogen receptors.

That said, when you talk to individuals who dabble in higher doses of exogenous Growth Hormone use, they sometimes report increased gyno development rates. This is theoretically possible with MK 677 as well.

If you do experience any severe side effects while taking MK 677, be sure to stop taking the product. And consider looking at a safer, legal, and natural alternative like IBUTA 677.

IBUTA 677 is an all-natural, safe, and legal, risk-free supplement intended to imitate the benefits of Ibutamoren MK 677 that delivers key ingredients that have been shown to increase HGH and muscle mass.

5. Diabetes (Extreme)

We mentioned earlier that Growth hormones could cause an increased risk of insulin resistance. If this is taken too far and pushed too hard, it can lead to diabetes.

MK 677 has been linked to extreme diabetes.

This occurs when the body becomes resistant to the insulin produced by the pancreas. As a result, blood sugar levels can rise to dangerously high levels. If left untreated, extreme diabetes can lead to serious health complications, such as heart disease and kidney failure.

If you experience any of the above symptoms while taking MK 677, it is important to seek medical attention immediately.

6. Blood pressure

High blood pressure or hypertension is another potential side effect of Ibutamoren.

An increase in water retention from using MK 677 can place more pressure on the heart and lead to an increase in blood pressure. In some cases, this can be severe and may require medical attention.

If you experience any signs or symptoms of high blood pressure, such as a pounding headache, dizziness, or nausea, stop taking MK 677 and consult your doctor immediately.

While blood pressure is a potential side effect of MK 677, it is important to remember that everyone reacts differently to medications and supplements. Some people may not experience any side effects at all, while others may only experience mild side effects.

FAQS on MK 677 Side Effects

Is MK 677 safe?

MK 677 is safe, but like with any other supplement, it’s important to be mindful of dosage. Taking too much can be dangerous, so if you’re considering taking MK 677, it’s important to speak with a healthcare professional to make sure it’s the right fit for you.

Additionally, it’s worth noting that MK 677 should not be taken by those who have an underlying health condition. Doing so could trigger adverse effects. So if you have any health concerns, it’s best to steer clear of this supplement altogether.

Is MK 677 legal?

Much uncertainty surrounds the legal status of MK 677. The substance is currently unapproved by the FDA and is not available for human consumption in the United States, as it is under investigation as at when writing this. However, some bodybuilders and athletes have used it in an effort to increase muscle mass and strength.

Given the limited regulation surrounding 677, it’s difficult to say definitively whether it’s legal or not. If you’re considering using MK 677, be sure to consult with a medical professional first to weigh the risks and benefits.

Can MK 677 kill you?

No, MK 677 will not kill you. MK 677 is a growth hormone secretagogue that was created to treat growth hormone deficiency. The supplement works by increasing the levels of growth hormone in the body.

Growth hormone is important for the development and maintenance of various tissues in the body, including muscles, bones, and organs. Therefore, MK 677 can help to improve muscle mass, bone density, and organ function.

Can MK 677 cause diabetes?

Yes, there is a risk for insulin resistance with MK-677.

However, it’s important to note that not everyone who takes MK-677 will develop insulin resistance. Some people seem to be more sensitive to the drug than others. Additionally, it’s imperative that blood sugar levels are closely monitored while taking MK-677, as any significant increases in blood sugar could put someone at risk for developing diabetes.

Can MK 677 cause hair loss?

MK 677 does not cause hair loss, and may in fact help improve the condition of your skin and hair.

Can MK 677 cause cancer?

MK-677 or Ibutamoren does not cause cancer growth, but it will allow existing tumors to grow. It binds to the same receptor as IGF-1 (insulin-like growth factor 1), which is a hormone that is known to promote tumor growth. So while MK-677 won’t cause cancer, it could potentially make tumors grow faster if someone already has them.

Does MK 677 increase testosterone?

Yes, MK 677 can help to increase testosterone levels. This is because it helps to stimulate the release of growth hormone, which in turn can lead to an increase in testosterone production.

Additionally, MK 677 can also help to improve bone density and muscle mass, which can further contribute to increased testosterone levels.

Does MK 677 raise blood pressure?

Some people may experience an increase in blood pressure when taking MK 677, although this is not a common side effect of Ibutamoren. If you have pre-existing hypertension or are at risk for developing high blood pressure, it’s important to desist from taking it.

Does MK 677 increase libido?

MK 677 may boost libido and increase sexual desire in some people, though more research is needed to say for certain.

Can MK 677 cause erectile dysfunction?

No, it can’t. There is some evidence that MK 677 could help with erectile dysfunction. MK-677 can increase growth hormone and IGF-1 levels, which could potentially lead to improved blood flow and better erections.

Can MK 677 cause gyno?

Yes, MK 677 can potentially cause gyno (breast enlargement) in some individuals.

This is because it causes prolactin levels to rise, and prolactin is known to stimulate breast growth. So if you are susceptible to this side effect, it is something to be aware of.

Can MK 677 increase height?

A study published in the Journal of Clinical Endocrinology & Metabolism showed that MK 677 increases growth hormone secretion in healthy adults by approximately 700% (that’s a seven-fold increase).

So, while MK 677 won’t make you grow endlessly like “Jack and the Beanstalk”, it can help you achieve a modest increase in height. This is especially beneficial for people who are shorter than average and would like to add a few extra inches.

Can MK 677 cause acromegaly?

t depends. MK 677 is a growth hormone secretagogue, meaning it stimulates the release of growth hormone from the pituitary gland. Growth hormone is responsible for things like cell growth and regeneration, so in theory, MK 677 could cause acromegaly if it’s used over an extended period of time and results in too much growth hormone being released.

However, there haven’t been any clinical studies on MK 677 and acromegaly, so we don’t really know what the long-term effects of MK 677 might be.

Can MK 677 cause acne?

Collagen is the most abundant protein in the human body, making up approximately 80% of our skin. It’s what gives our skin its strength and elasticity. So, when we age, or when we suffer from certain medical conditions that impact collagen production, our skin can start to look loose and wrinkled.

MK 677 is a peptide that was originally developed to help people with growth hormone deficiencies.

But it’s also been shown to boost collagen production in the body. So, it stands to reason that using MK 677 could help improve the appearance of your skin by increasing collagen levels.

However, there’s no direct evidence that MK 677 causes acne.

Why does MK 677 cause lethargy?

While the cause of this lethargy is unknown, it may be due to the fact that MK-677 causes a significant increase in levels of IGF-1. IGF-1 is a hormone that is known to promote growth and regeneration. However, high levels of IGF-1 can also cause adverse side effects such as lethargy, edema (swelling), and carpal tunnel syndrome.

Or probably because it increases levels of serotonin in the brain.

Serotonin is a neurotransmitter that is associated with feelings of happiness and well-being, and too much serotonin can cause drowsiness and fatigue.

It is also possible that lethargy is caused by a change in sleep patterns.

MK-677 has been shown to increase levels of growth hormone, which can lead to changes in sleep patterns. Growth hormone is secreted in pulses throughout the night, and these pulses are thought to be responsible for the deep, restful sleep that is crucial for muscle growth and repair.

Whatever the cause of the lethargy, it is important to remember that it is only a temporary side effect.

Why is MK 677 illegal??

MK-677 is not entirely illegal. It is, however, prohibited in sports competitions, the same way as anabolic steroids – according to the World Anti-Doping Agency (WADA), and therefore its possession and use by athletes competing in WADA-sanctioned events are against the rules.

As an Investigational New Drug (IND), MK-677 has not been approved for human use by the U.S.

Food and Drug Administration (FDA). Although it is not currently illegal to possess or use MK-677 in the United States, this could change if it were ever approved by the FDA for human use.

At that point, it would be classified as a drug and would be subject to regulation under the Controlled Substances Act (CSA).

What’s a better alternative to Mk 677? (without side effects)

While MK 677 is perfectly legal to purchase as a research chemical, its potential side effects make it slightly less attractive to some people. If you are looking for something that is more obtainable but will still cause an increase in Growth Hormone levels, you could look at IBUTA 677.


There are a few things that make IBUTA 677 stand out from MK 677.

For one, IBUTA 677 contains 100% all-natural ingredients.

This means that there are no synthetic fillers or binders; everything in the formula is designed to work together to support optimal health and performance.

Additionally, because all of the ingredients are natural, there are no known side effects associated with IBUTA 677 use.

This is in contrast to MK 677, which has been linked to some negative side effects we covered on this page.

IBUTA 677 has also been shown to improve mental focus and cognitive function, increase strength, ,fast recovery time and muscle mass.

Final Thoughts

MK 677 side effects are largely determined by the dosage. The lower the dose, the fewer and milder the side effects. Sometimes it could depend on some other factors like an underlying medical condition, diet, or tolerance.

For most people, however, water retention is the main issue to watch out for.

If you experience excessive water retention or any other adverse reaction while taking MK 677, stop using it and consider our recommended alternative – IBUTA 677.

Have you tried MK 677? What has been your experience with it?

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