PhenQ vs. Phen375: What’s Best for Weight Loss?

January 10, 2024 |

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Phen375 was introduced as an over-the-counter alternative to the prescription weight loss pill “Phentermine 37.5”.

Similarly, PhenQ, another OTC fat burner, serves the same purpose as Phentermine but without messing with your nervous system and causing deadly side effects.

While both products promise similar weight loss benefits, only one of them has a reputable market base, while the other is nowhere to be found, neither online nor in-store.

YES, Phen375 was retracted from stores, and its manufacture was halted because of the continuous poor user reviews!

It also got rated F by the Business Bureau (BBB) because of the unresponsive customer service, which never got back to the buyers after charging their credit cards in full for Phen375’s purchase.

So, for the PhenQ vs. Phen375 comparison, the former is the winner.

Our Pick

PhenQ – 5 in 1 Fat Burner

Our tried and tested weight loss pill not only burns fat but also prevents it from re-accumulating and keeps the untimely cravings at bay!

What is PhenQ & How Does it Work?

PhenQ is a diet pill that targets the root cause of weight gain and prevents you from indulging in behaviors and eating patterns that got you to this point in the first place.

How so? By BOOSTING your energies, FIRING UP your metabolism, and keeping your stomach filled with its fiber content for extended periods!

Boosted energy –> Better Workouts, More Focus

Fired-up Metabolism –> Increased Thermogenesis, Faster Fat Burn

Increased Stiateity –> Lesser Craving, Decrease in Calorie Intake

PhenQ Pros

  • Blocks the formation of new fat
  • Eliminates excess fat
  • Suppresses appetite
  • 5 in 1 action
  • Allergen (soy, gluten, dairy) free
  • Vegan and vegetarian
  • Produced in FDA and GMP-compliant facilities
  • 60-day money-back guarantee

PhenQ Cons

  • Not for pregnant or nursing women.
  • Intended for ages above 18 years.

What is Phen375 & How Does it Work?

Manufacturers of Phen375 claim that it helps curb hunger, increase metabolism rate, and get rid of aggressive fat.

It had ingredients like L-carnitine, caffeine, bitter orange, coleus forskohlii, etc.

Among these, coleus forskohlii enhances fat breakdown in the body. Likewise, L-carnitine mobilizes fat and promotes its utilization as an energy source. Furthermore, the bitter orange and caffeine curb appetite.

Phen375 Pros

  • Reduces fat
  • Prevents hunger pangs
  • Gives energy
  • Vegan and vegetarian
  • No dairy allergens
  • Manufactured in FDA-registered and cGMP/NSF facilities
  • 60-day money-back guarantee.

Phen375 Cons

  • Not for pregnant and nursing women
  • Not for ages below 18 years
  • Contains FDA and NCAA-banned substance synephrine
  • Withdrawn from market
  • Non-existent Customer Support

No link here 🙁 as original Phen375 is no longer available.

Phen375 Vs. PhenQ – Product Comparison

Brand Reputation

PhenQ, a dietary supplement, is manufactured and distributed by Wolfson Berg Ltd, a UK-based company renowned for crafting leading health and wellness products for more than 15 years.

In contrast, since Phen375 has been discontinued, therefore, the name of its official makers is unclear now.

Key Ingredients

The benefits of using PhenQ for weight loss can be attributed to ingredients like α-Lacys Reset, capsimax powder, caffeine, nopal fiber, L-carnitine, etc.

In comparison, Phen375 imparts its effect with ingredients like L-carnitine, caffeine anhydrous, coleus forskohlii, bitter orange, etc.

Both PhenQ and Phen374 use L-carnitine to help you flatten your belly. It can help energize you by utilizing the excess fat stored in your body, which may fuel both your workout and decrease your waist width. 

Moreover, both contain caffeine that may help to unload excess fat and ramp up your energy levels.

The manufacturers had added caffeine anhydrous, which is the concentrated form of caffeine and may be more effective in promoting fat oxidation and increasing metabolism rate and focus.

Common Ingredients 

  • Caffeine Anhydrous
  • Capsaicin Compounds
  • Chromium picolinate

PhenQ Unique Ingredients

  • L-carnitine fumarate
  • α-LACY’s reset
  • Nopal
  • InnoSlim

Phen375 Unique Ingredients 

  • L-carnitine L-tartrate
  • Bitter Orange
  • Coleus Forskohlii root extract
  • Dendrobium Nobile extract

Dosage Regime

In the case of PhenQ, you have to take one pill in the morning after breakfast and another after lunch but before 3 pm.

However, Phen374 used to allow one pill less and you only had to take a single pill after breakfast.


PhenQ is a decade-old product manufactured by esteemed Wolfson Brands Ltd. Both supplements are based on natural ingredients and contain stimulants.

Nonetheless, Phen375 had an easier dosage regime requiring you to take only one pill per day compared to 2 PhenQ pills daily.

PhenQ CT

Phen375 or PhenQ – Which Is Best For Weight Loss?

Both Eliminate Excess Fat

  • Both contain Capsaicin Compounds Which Melt The Fat Away

The capsimax powder in PhenQ and the cayenne pepper in Phen375 contain ‘capsinoids’ that trigger fat loss.

However, the best part about PhenQ is that these hot pepper compounds are encapsulated in beads which mitigates their risk of irritating the stomach.

In one study, its weight loss benefit was most notable in obese individuals with a body mass index (BMI) over 25.

  • Both Contain Caffeine To Get Rid Of Fat

Coming towards caffeine is also a staple ingredient in energy drinks because it stimulates the central nervous system to increase alertness and causes energy surges.

Additionally, 13 Randomized Control trials have reported that caffeine intake directly corresponds to a mean reduction in fat mass, weight, and overall BMI.

  • Both Have L-carnitine, Which Converts Fat Into Energy

L-carnitine is an amino acid derivative that drives the conversion of fats into energy and boosts heart, brain, and muscle function hence, overall well-being.

A meta-analysis reviewed nine studies and concluded that carnitine supplementation significantly reduced body weight in the studied subjects.

PhenQ Imparts Stronger Appetite Suppression with  Nopal

  • Both Supplements Promote Satiety And Prevent Cravings

Both Phen375 and PhenQ employ the stimulant effect of caffeine to make you feel full. This happens because the stimulation of the sympathetic nervous system delays gastric emptying.

Apart from that both supplements contain L-carnitine, and chromium picolinate which stabilize blood sugar levels and prevent carb and sugar cravings.

  • PhenQ Causes Fullness With Nopal Fiber

PhenQ, which exclusively contains nopal (a vegetable) fiber has two major benefits: it promotes satiety and nourishes the good gut microbes to help you attain a healthy figure. 

On a side note,  Phen375 also has an additional ingredient coleus forskohlii but there is only limited evidence to support its potential to control hunger.

  • PhenQ’s Α-Lacys Reset Eliminates The Risk Of Muscle Loss

The L-carnitine in both supplements aids muscle recovery after exercise and prevents muscle soreness which helps to preserve lean muscles.

However, PhenQ additionally contains α-Lacys Reset which is a scientifically acclaimed combination of ALA (Alpha Lipoic Acid) and cysteine that sheds the fat only while retaining the muscle mass.

The clinical trial in which it was evaluated reported that it caused the participants to lose 7.34% of their body fat and 3.44% of their body weight.


Both PhenQ and Phen375 have similar benefits on fat loss, hunger reduction, and lean muscle preservation.

But PhenQ contains some additional ingredients like nopal and α-Lacys Reset which enhances these effects.

Additionally, the unavailability of Phen375 enables an easy win for PhenQ as the more effective supplement.

PhenQ CT

PhenQ Vs. Phen375 – Which One Is Safer?

PhenQ Side Effects

PhenQ may cause mild issues like headache, digestive issues, nausea, anxiety and digestion problems, restlessness, anxiety, and trouble sleeping.

Correspondingly, Ginger Conell shared on Trustpilot that she suffered from horrible pain and bloating after taking PhenQ for three days.

Phen375 Side Effects

Some side effects caused by Phen374 include lightheadedness, headaches, restlessness, nausea, gastrointestinal upset, increased hair growth, oily skin, and high blood pressure.


PhenQ is undeniably the safer product because it has a better safety ranking and milder side effects.

PhenQ CT

PhenQ or Phen375 – Which One is More Affordable?

PhenQ – Where To Buy & Price

I recommend ordering PhenQ from its official store, as it offers a 60-day money-back guarantee and the customer support is also great!

They ACTUALLY listen to your concerns and answer your queries patiently without rushing you into making a purchase

(I know from how they tolerated my inquisitive being well 😉 )

You can purchase one bottle of PhenQ for $69.99, which contains 60 tablets, which are enough for a month.

Phen375 – Where To Buy & Price

You could buy a bottle of Phen375 for $65.95 that contained 30 tablets and lasted a whole month.

However, you can’t purchase it now as its official website where it was available is inaccessible now.


Even though Phen375 allows greater savings and is $4 cheaper than PhenQ, you can not buy it anymore. Therefore, if you require a weight loss aid PhenQ is your best bet. 

PhenQ CT

Which Weight Loss Supplement is Best?

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