PhenQ Vs. Rybelsus – What’s Best for Weight Loss?

January 10, 2024 |

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PhenQ and Rybelsus provide similar weight loss results, though their ingredients’ types and safety profiles do not match. 

Correspondingly, Rybelsus can cause severe side effects, which is why it is not sold over the counter. Also, weight loss is not its primary effect, as is the case for PhenQ.

That’s why it is imperative that you look into their complete ingredient lists and user feedback before you decide on one, as I have done in this elaborate comparison guide.

Best Choice

PhenQ

Overall rating: 4.9/5
  • Over-the-counter weight loss pill
  • Made with natural plant extracts
  • Increases fat burn and decreases fat storage
  • Lowers hunger hormone secretion to prevent binge eating
  • Has only mild side effects that go away soon
  • Can only be purchased from the official website
Best Value

Rybelsus

Overall rating: 3.8/5
  • Prescription-only anti-diabetic pill
  • Based on a synthetic complex (Semaglutide)
  • Mild upregulation of fat metabolism
  • Induces fullness to suppress food cravings
  • Serious side effects like pancreatitis and gallbladder issues
  • Not available for purchase on the official website.

What Is PhenQ & How Does It Work?

PhenQ is a weight loss supplement made with natural ingredients. It includes compounds that increase heat production in the body, promote the formation of brown adipose tissue, and trigger the AMPK hormone. 

All these mechanisms, in turn, lead to faster fat oxidation and melting of stored fat lumps.

3 PhenQ Bottles

Another way PhenQ ingredients help with weight loss is by promoting satiety to reduce binge eating and random munching.

PhenQ Pros

  • Uses 3 effective mechanisms to suppress appetite
  • Promotes fat oxidation with natural compounds
  • Reduces fat absorption and storage
  • Natural, vegan-friendly, and GMP-certified pills
  • 60-day money-back guarantee

PhenQ Cons

  • Not available for purchase at local stores or pharmacies

What Is Rybelsus & How Does It Work?

Rybelsus is an oral prescription-only medicine that has been formulated for diabetes control. But, because it lowers insulin resistance and upregulates metabolism, people often use it for weight management. 

rybelsus

Its active ingredient, semaglutide, is a GLP-1 antagonist that mimics natural GLP-1 hormone, lowering insulin resistance and stabilizing blood glucose. In turn, these effects induce satiety and increase fat consumption.

Ryblesus Pros

  • Helps with diabetes management
  • Reduces insulin resistance to upregulate fat metabolism
  • Makes you feel satisfied with less food

Rybelsus Cons

  • Not available without a prescription
  • Way more expensive than PhenQ
  • Serious side effects (changes in vision, pancreatitis, renal impairment)

The price for Rybelsus varies according to your insurance plan. Plus, to buy it online, you would need to submit your doctor’s prescription first. So, no link here, sorry. 🙁

PhenQ Vs. Rybelsus– Product Comparison

Brand Reputation

PhenQ is a product of Wolfson Brands, a multinational business manufacturing supplements like weight loss pills, probiotic capsules, pre-workout powders, mass gainers, and testosterone uplifters.

This company is present on the market for over two decades and has a global consumer base.

In contrast, the manufacturer of Rybelsus, Novo Nordisk, is a pharma founded in the 1920s, envisioning better insulin regulation and diabetes management. Semaglutide is their patented compound used for both anti-diabetic and anti-obesity medicines.

Besides Rubelsus, Novo Nordisk also produces weight loss medicines like Ozempic, Wegovy, and Saxenda.

Key Ingredients

PhenQ is a combination of 13 natural components. Its key fat burner ingredients are caffeine, l-carnitine tartrate, alpha lipoic acid, capsimax, and Nopal cactus extracts. 

Herbal extracts like Capsimax powder, black pepper, and Nopal cactus extract also keep your body from accumulating new fats.

The ingredients that promote satiety and keep cravings off are cysteine (from α-Lacy’s reset), Innoslim, and Nopal fibers.

On the other side, Rybelsus has only one active ingredient, semaglutide. It is a patented lab-synthesized compound that mimics the natural GLP-1 hormone, triggering insulin production and increasing fat oxidation.

Common Ingredients:

  • None

PhenQ Unique Ingredients:

  • L-carnitine L-tartrate
  • Innoslim
  • Caffeine Anhydrous
  • Capsimax Powder
  • ɑ-Lacy’s Reset  
  • Nopal Cactus
  • Piperine
  • Chromium picolinate
  • Vitamin (B3, B6, and B12)
  • Copper
  • Iodine

Rybelsus Unique Ingredients:

  • Semaglutide

Dosage Regimen

You should take 2 PhenQ pills daily, preferably with the first 2 meals of the day. Because if you have them too late in the day, their caffeine content may disturb your sleep pattern.

In contrast, Rybelsus is a once-daily medicine. Take it first thing in the morning with a few sips of water (not more than 4 ounces). Afterward, wait at least 30 minutes before you take the breakfast so that Rybelsus can properly absorb into blood and start working.

verdict

Although both brands represent reputable drug producers, PhenQ is a sub-brand of a popular fitness supplement company, while Rybelsus comes from a pharma company focusing on diabetes management. Owing to this, these pills have no common ingredient. 

The dosage routine is relatively simpler for Rybelsus as it is a once-daily pill.

PhenQ CT

PhenQ Or Rybelsus- Which Is Best For Weight Loss?

PhenQ Boosts Stimulation and Thermogenesis To Speed Up Fat Loss

Unlike Rybelsus, which is primarily focused on lowering AC1 scores, PhenQ is exclusively made to cut excessive fat on your body.

Firstly, it jumpstarts metabolism with a stimulation burst (from caffeine), which is further supported by non-stimulatory thermogenesis and the conversion of stored white fatty acids to easily consumable brown fats (from Capsimax and black pepper extracts).

Thermogenesis is the production of heat inside the body, which speeds up metabolic reactions and makes your body consume food (and stored fats) faster.

As a result, you not only get rid of extra fats but also feel more energetic and healthy.

But that’s not all.

PhenQ also helps with fat burn by actively transporting fatty acids from cellular storehouses to the oxidizing sites (l-carnitine). 

Its efficacy is proven by real user feedback on different platforms like Reddit, Quora, and Trustpilot. For example, Douglas reported losing 20 lbs in three months with PhenQ.

In contrast, Rybelsus helps with fat burn in one way only.

Being a GLP-1 agonist, semaglutide activates the AMPK pathway. AMPK is a cellular enzyme that makes your body burn more calories to extract energy.

When you are on a restricted-calorie diet, it forces your body to consume stored fats to provide additional calories for this process.

Rybelsus’s Anti-diabetic Effects Also Promote Weight Loss

As I mentioned earlier, Rybelsus is not a diet pill but helps with weight loss as a secondary benefit.

Semaglutide makes your body produce more insulin. This insulin surge normalizes high blood sugar and also promotes satiety. As a result, you start feeling full with smaller meals than you normally eat. 

This mechanism works for diabetic and pre-diabetic people as well because GLP-1 agonists make your body more receptive to insulin.

Also, Rybelsus has a positive effect on fat metabolism, as explained above.

PhenQ Also Improves Insulin sensitivity, but by Using A Herbal Preparation

Innoslim, a proprietary blend added to the PhenQ recipe, makes its efficacy comparable to Rybelsus.
Like Semaglutide, it also lowers insulin resistance and triggers the AMPK enzyme. In turn,

  •  Lowered insulin resistance leads to stabilized glycemic levels, increased satiety, and lesser sugar cravings. 
  • And AMPK enzyme increases energy expenditure and fast paces fat consumption.

Due to these effects, PhenQ also proves helpful for diabetic individuals who struggle to lose weight due to high insulin resistance, as Marlene’s Trustpilot review proves.

Your Muscles Are Protected With PhenQ 

Muscle retention is the key to healthy and long-lasting weight loss. And PhenQ will help you preserve lean body mass while dieting with ingredients like alpha lipoic acid, B vitamins, and l-carnitine.

Niacin (vitamin B3) offers dual benefits in this case. 

On one side, it strengthens muscles, making them resist degradation. And on the other side, it increases energy extraction in muscle tissues, making them eat up fatty acids deposited adjacent to them.

L-carnitine tartrate has a similar function, while ALA affects gene expression to slow down protein degradation in muscles.

verdict

PhenQ is hands down a more potent weight loss solution as it restricts new fat deposition, in addition to appetite suppression. Whereas, Rybelsus has no such benefit since it is primarily an anti-diabetes drug.

PhenQ CT

PhenQ And Rybelsus Side Effects – Which Is Safer?

PhenQ Side Effects

PhenQ side effects are mostly related to the gut. For example, diarrhea, nausea, and bloating. These troubles arise because your gut walls are irritated by the potent thermogenic components of the drug. 

However, most of these symptoms disappear within a week or so as your gut becomes familiar with the new ingredients.

Besides that, some users may experience headaches and sleep issues after taking these pills due to caffeine sensitivity. 

(If you are one of them, you can use the caffeine-free version of PhenQ. Learn all about it here.)

Rybelsus Side Effects

The official Rybelsus website cautions that this drug can cause mild and serious side effects as other semaglutide medicines do.

However, user feedback shows that the side effects intensity is lesser than what they felt with ozempic or wegovy injections.

  • Common side effects include nausea, diarrhea, abdominal pain, vomiting and constipation. 
  • Possible serious side effects of these pills are pancreatitis, hypoglycemia, vision changes, kidney issues, gall bladder problems, and allergic reactions. 

Besides that, I found some users saying they feel a metallic aftertaste in their mouth with this drug. Others complained of tiredness and feeling sleepy all day, which is possibly a result of hypoglycemia (low blood sugar).

An interesting thing I found about this drug’s effect is that some individuals noticed Rybelsus decreased their anxiety but made it worse for others.

verdict

PhenQ is a safer drug as none of its ingredients are associated with severe side effects like semaglutide. 

PhenQ CT

Rybelsus Vs. PhenQ – Which One Is More Affordable?

 PhenQ – Where To Buy & Price

PhenQ is sold exclusively through the brand’s official website. One bottle costs $69.99 and is enough for 1 month with the recommended dosage.

But the price drops if you opt for the bundle deals. For example,

  • A pack of 3 bottles costs $139.99
  • While a pack of 5 bottles costs $209.99

Also, the shipping is free, and you can return the package for a 100% refund within 60 days if you don’t get the results.

Rybelsus – Where To Buy & Price

Rybelsus is available on prescription from local and online pharmacies. It’s a budget-friendly drug ONLY if your insurance covers it (costs as low as $10 for a 30-day supply). 

Otherwise, it will cost you $935.77 per bottle (30 pills).

verdict

PhenQ costs about 12 times less than Rybelsus. But if you own a health insurance plan covering GLP-1 agonists, the prescription drug becomes cheaper. 

PhenQ CT

FAQs

What drug is comparable to Rybelsus?

Ozempic and Wegovy injections work similarly to Rybelsus as all three contain the same active ingredient, semaglutide. 

Is Rybelsus a weight loss pill?

No, it is an anti-diabetic drug made to keep AC1 scores lower. 

But its auxiliary effects, like reduction of appetite and AMPK activation, also help with weight loss, which lures many to use it for getting rid of extra pounds.

How quickly does Rybelsus work for weight loss?

Most users start noticing Rybelsus weight loss results within the first 2 weeks. But for considerable weight reduction, you may need to wait 3-6 months, depending on your diet and physical activity.  

How much weight will I lose on Rybelsus?

Clinical trials suggest that Rybelsus causes an average weight drop of 8-10 lbs in six months.

But it is highly subjective to your diet, exercise, and natural metabolism. User feedback from Reddit fitness discussion shows that you can also lose 20 lbs or higher with Rybelsus if you combine it with a healthy diet and exercise.

Which Weight Loss Supplement Is Best?

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